HitPredict

Interactor 1: VP37A (Q8NEZ2)
Vacuolar protein sorting-associated protein 37A (hVps37A) (ESCRT-I complex subunit VPS37A) (Hepatocellular carcinoma-related protein 1)
Gene: VPS37A

Interactor 2: VPS28 (Q9UK41)
Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28)
Gene: VPS28

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 15240819, 26186194, 28514442, 31519728, 33961781, 35271311, 21757351
Identification Methods pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Mod_r~VPS28
Common GO terms GO:0000813 - ESCRT I complex
GO:0005829 - cytosol
GO:0010008 - endosome membrane
GO:0016236 - macroautophagy
GO:0031902 - late endosome membrane
and 5 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 397
Hs

1 221
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Ce
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024