HitPredict

Interactor 1: HIP1 (O00291)
Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I)
Gene: HIP1

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.744

Property	Details
Experiments	26496610, 11889126, 23836884, 11517213, 11604514, 11532990, 22820750
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0030136 - clathrin-coated vesicle GO:0032051 - clathrin light chain binding GO:0048268 - clathrin coat assembly
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1037 Hs			1 1675
+	Hs
		255314 HIP1R_HUMAN (8-1011): 2.9e-63: 235: 49.66		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		724778 MYH9_HUMAN (103-1037): 7.13e-48: 189: 8.73		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		124382 HIP1_HUMAN (1-1037): 1.89e-81: 288: 100.00		CLH2_HUMAN (1-1634): 0: 2869: 85.01
+	Sc
		604378 SLA2_YEAST (37-1009): 5.36e-47: 184: 19.19		CLH_YEAST (5-1648): 0: 2443: 49.79