Interactor 1: DOCK8 (Q8NF50)
Dedicator of cytokinesis protein 8
Gene: DOCK8

Interactor 2: DOCK8 (Q8NF50)
Dedicator of cytokinesis protein 8
Gene: DOCK8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 25416956
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DHR-2_Lobe_A~DHR-2_Lobe_A, DHR-2_Lobe_A~DHR-2_Lobe_B, DHR-2_Lobe_B~DHR-2_Lobe_C, DHR-2_Lobe_C~DHR-2_Lobe_C, DOCK-C2~DOCK-C2
Common GO terms GO:0001771 - immunological synapse formation
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 13 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 2099
Hs

1 2099
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024