HitPredict

Interactor 1: DOCK8 (Q8NF50)
Dedicator of cytokinesis protein 8
Gene: DOCK8

Interactor 2: MOB1A (Q9H8S9)
MOB kinase activator 1A (Mob1 alpha) (Mob1A) (Mob1 homolog 1B) (Mps one binder kinase activator-like 1B)
Gene: MOB1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37536630, 24255178
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2099 Hs			1 216
+	Hs
		1185489 DOCK8_HUMAN (1-2099): 0: 2775: 100.00		MOB1B_HUMAN (1-216): 5.52e-119: 338: 95.83
+	Hs
		1298521 DOCK7_HUMAN (7-2092): 0: 2471: 55.37		MOB1A_HUMAN (1-216): 3.44e-119: 339: 100.00
+	Hs
		1185495 DOCK7_HUMAN (7-2092): 0: 2471: 55.37		MOB1B_HUMAN (1-216): 5.52e-119: 338: 95.83
+	Hs
		1198334 DOCK7_HUMAN (7-2092): 0: 2471: 55.37		MOB3B_HUMAN (5-212): 2.16e-108: 311: 52.63
+	Hs
		1174284 DOCK7_HUMAN (7-2092): 0: 2471: 55.37		MOB3C_HUMAN (5-212): 7.65e-106: 305: 50.72
+	Hs
		1293667 DOCK6_HUMAN (4-2092): 0: 2401: 51.16		MOB1A_HUMAN (1-216): 3.44e-119: 339: 100.00
+	Hs
		1185492 DOCK6_HUMAN (4-2092): 0: 2401: 51.16		MOB1B_HUMAN (1-216): 5.52e-119: 338: 95.83
+	Hs
		1174281 DOCK6_HUMAN (4-2092): 0: 2401: 51.16		MOB3C_HUMAN (5-212): 7.65e-106: 305: 50.72
+	Hs
		1127522 DOC11_HUMAN (22-177): 2.25e-43: 176: 22.50		MOB3B_HUMAN (5-212): 2.16e-108: 311: 52.63
+	Hs
		1127519 DOC11_HUMAN (22-177): 2.25e-43: 176: 22.50		MOB3C_HUMAN (5-212): 7.65e-106: 305: 50.72
+	Hs
		1198335 DOCK9_HUMAN (5-177): 2.21e-40: 167: 19.89		MOB3B_HUMAN (5-212): 2.16e-108: 311: 52.63