HitPredict

Interactor 1: SYNE1 (Q8NF91)
Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)
Gene: SYNE1

Interactor 2: SYNE1 (Q8NF91)
Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)
Gene: SYNE1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.740

The method score is based on:

Property Details
Experiments 12163176
Identification Methods two hybrid, pull down, far western blotting
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, CH~Spectrin, Spectrin~Spectrin
Common GO terms GO:0000932 - P-body
GO:0002053 - positive regulation of mesenchymal cell proliferation
GO:0003723 - RNA binding
GO:0003779 - actin binding
GO:0005102 - signaling receptor binding
and 37 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 8797
Hs

1 8797
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024