HitPredict

Interactor 1: SYNE1 (Q8NF91)
Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)
Gene: SYNE1

Interactor 2: CEP63 (Q96MT8)
Centrosomal protein of 63 kDa (Cep63)
Gene: CEP63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.50	0.526

Property	Details
Experiments	17043677, unassigned1973
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 8797 Hs			1 703
+	Hs
		149072 SYNE1_HUMAN (1-8797): 0: 1912: 100.00		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		1137099 SYNE1_HUMAN (1-8797): 0: 1912: 100.00		CROCC_HUMAN (102-701): 1.82e-12: 73.2: 9.08
+	Hs
		1263708 SYNE2_HUMAN (2840-8740): 2.87e-69: 265: 8.94		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		164656 SPTN2_HUMAN (18-355): 7.94e-49: 197: 39.12		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		974132 DYST_HUMAN (12-1547): 1.58e-42: 177: 13.83		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		1068639 PLEC_HUMAN (7019-8757): 8.37e-37: 158: 9.89		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		149115 SYNE2_HUMAN (2840-8740): 2.87e-69: 265: 8.94		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		164575 SPTN2_HUMAN (18-355): 7.94e-49: 197: 39.12		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148142 SPTN2_HUMAN (18-355): 7.94e-49: 197: 39.12		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		110636 H3BPE1_HUMAN (15-1509): 2.18e-44: 183: 14.24		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		164647 SPTN2_HUMAN (18-355): 7.94e-49: 197: 39.12		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		724786 DYST_HUMAN (12-1547): 1.58e-42: 177: 13.83		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148330 SPTB1_HUMAN (18-445): 9.3e-44: 181: 32.95		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		149277 SPTN4_HUMAN (18-354): 7.24e-42: 174: 35.10		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		974117 DYST_HUMAN (12-1547): 1.58e-42: 177: 13.83		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		724839 PLEC_HUMAN (7019-8757): 8.37e-37: 158: 9.89		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		1068548 PLEC_HUMAN (7019-8757): 8.37e-37: 158: 9.89		GRDN_HUMAN (150-697): 6.94e-17: 87.5: 12.91
+	Hs
		148841 PLEC_HUMAN (7019-8757): 8.37e-37: 158: 9.89		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		974137 DYST_HUMAN (12-1547): 1.58e-42: 177: 13.83		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94
+	Hs
		1068617 PLEC_HUMAN (7019-8757): 8.37e-37: 158: 9.89		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15