HitPredict

Interactor 1: NUP43 (Q8NFH3)
Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42)
Gene: NUP43

Interactor 2: MED12 (Q93074)
Mediator of RNA polymerase II transcription subunit 12 (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (Mediator complex subunit 12) (OPA-containing protein) (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Trinucleotide repeat-containing gene 11 protein)
Gene: MED12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 2177
+	Hs
		1274325 FBXW7_HUMAN (3-371): 2.85e-70: 235: 12.30		MED12_HUMAN (1-2177): 0: 2488: 100.00
+	Hs
		1274327 SNR40_HUMAN (249-378): 1.1e-25: 107: 17.04		MED12_HUMAN (1-2177): 0: 2488: 100.00
+	Hs
		1281353 FBXW7_HUMAN (3-371): 2.85e-70: 235: 12.30		DIDO1_HUMAN (1479-2099): 1.5e-18: 95.4: 10.74
+	Hs
		1017326 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		BPTF_HUMAN (1686-2176): 1.04e-14: 83.1: 11.51
+	Hs
		1244268 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		ARI1B_HUMAN (1839-2172): 5.1e-10: 67.3: 14.20
+	Hs
		1057775 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		NCOA6_HUMAN (1716-2173): 1.71e-09: 65.7: 11.91
+	Hs
		1244435 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		EP400_HUMAN (1812-2174): 7.89e-09: 63.4: 17.63
+	Hs
		1057782 FBXW7_HUMAN (3-371): 2.85e-70: 235: 12.30		NCOA6_HUMAN (1716-2173): 1.71e-09: 65.7: 11.91
+	Hs
		1281318 FBXW7_HUMAN (3-371): 2.85e-70: 235: 12.30		EP400_HUMAN (1812-2174): 7.89e-09: 63.4: 17.63
+	Hs
		903374 WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24		KMT2C_HUMAN (1619-2174): 8.59e-16: 86.5: 10.80
+	Mm
		903669 WDR5_MOUSE (3-289): 4.3e-58: 193: 14.24		KMT2C_MOUSE (1774-2158): 4.99e-12: 74.2: 10.20
+	Hs
		302275 WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24		SC31A_HUMAN (1897-2176): 1.29e-11: 72.3: 11.54
+	Hs
		903405 WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24		CBP_HUMAN (1582-2176): 2.69e-11: 71.5: 13.45
+	Hs
		903229 WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24		NCOA6_HUMAN (1716-2173): 1.71e-09: 65.7: 11.91
+	Hs
		1244287 SNR40_HUMAN (249-378): 1.1e-25: 107: 17.04		ARI1B_HUMAN (1839-2172): 5.1e-10: 67.3: 14.20
+	Hs
		997694 RBBP4_HUMAN (216-378): 3.53e-19: 90.3: 13.59		BPTF_HUMAN (1686-2176): 1.04e-14: 83.1: 11.51
+	Hs
		1017306 RBBP7_HUMAN (216-378): 1.89e-18: 88.3: 14.13		BPTF_HUMAN (1686-2176): 1.04e-14: 83.1: 11.51
+	Hs
		1288242 SNR40_HUMAN (249-378): 1.1e-25: 107: 17.04		EP400_HUMAN (1812-2174): 7.89e-09: 63.4: 17.63
+	Hs
		997838 RBBP4_HUMAN (216-378): 3.53e-19: 90.3: 13.59		CBP_HUMAN (1582-2176): 2.69e-11: 71.5: 13.45
+	Hs
		997936 RBBP4_HUMAN (216-378): 3.53e-19: 90.3: 13.59		CHD7_HUMAN (1825-2174): 2.18e-10: 68.8: 10.05