HitPredict

Interactor 1: NUP43 (Q8NFH3)
Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42)
Gene: NUP43

Interactor 2: P121A (Q96HA1)
Nuclear envelope pore membrane protein POM 121 (Nuclear envelope pore membrane protein POM 121A) (Nucleoporin Nup121) (Pore membrane protein of 121 kDa)
Gene: POM121

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24927568, 32344865
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0006913 - nucleocytoplasmic transport GO:0051028 - mRNA transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 1249
+	Hs
		1281391 FBXW7_HUMAN (3-371): 2.85e-70: 235: 12.30		PRR36_HUMAN (397-1246): 3.17e-28: 125: 11.28
+	Hs
		1170071 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		SRCAP_HUMAN (13-936): 9.28e-21: 101: 10.61
+	Hs
		858014 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		NUP98_HUMAN (828-1223): 9.68e-19: 95.1: 19.77
+	Hs
		727289 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		NU214_HUMAN (91-1211): 3.61e-15: 83.5: 12.90
+	Hs
		1244598 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		PRC2C_HUMAN (2-1138): 9.15e-15: 82.1: 9.62
+	Hs
		1244268 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		ARI1B_HUMAN (128-1241): 3.11e-14: 80.3: 7.91
+	Hs
		1056899 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		MDC1_HUMAN (87-1249): 8.98e-14: 78.8: 9.17
+	Hs
		72751 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		B4DET5_HUMAN (79-778): 1.43e-13: 77.5: 11.14
+	Hs
		1057775 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		NCOA6_HUMAN (362-1248): 1.45e-11: 71.5: 8.61
+	Hs
		1057782 FBXW7_HUMAN (3-371): 2.85e-70: 235: 12.30		NCOA6_HUMAN (362-1248): 1.45e-11: 71.5: 8.61
+	Hs
		1244573 NUP43_HUMAN (1-380): 6.08e-77: 243: 95.80		SRRM2_HUMAN (3-891): 8.36e-09: 62.5: 10.62
+	Hs
		857957 WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24		NUP98_HUMAN (828-1223): 9.68e-19: 95.1: 19.77
+	Mm
		903669 WDR5_MOUSE (3-289): 4.3e-58: 193: 14.24		KMT2C_MOUSE (4-816): 5.48e-18: 92.6: 9.58
+	Dm
		1370339 FBXW7_DROME (102-377): 2.21e-60: 212: 14.80		Q9VLS7_DROME (1-721): 4.34e-11: 69.9: 6.70
+	Hs
		903374 WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24		KMT2C_HUMAN (570-1226): 5.4e-15: 82.9: 13.37
+	Hs
		903229 WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24		NCOA6_HUMAN (362-1248): 1.45e-11: 71.5: 8.61
+	Hs
		903450 WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24		CIC_HUMAN (128-1161): 2.11e-09: 64.5: 9.81
+	Hs
		793042 LIS1_HUMAN (5-248): 1.25e-48: 171: 12.06		SRRM2_HUMAN (3-891): 8.36e-09: 62.5: 10.62
+	Hs
		72754 SNR40_HUMAN (249-378): 1.1e-25: 107: 17.04		B4DET5_HUMAN (79-778): 1.43e-13: 77.5: 11.14
+	Dm
		1358850 WDS_DROME (255-379): 3.32e-27: 112: 19.53		NUP98_DROME (1014-1232): 3.69e-09: 63.6: 25.55