HitPredict

Interactor 1: KBTB8 (Q8NFY9)
Kelch repeat and BTB domain-containing protein 8 (T-cell activation kelch repeat protein) (TA-KRP)
Gene: KBTBD8

Interactor 2: FXL17 (Q9UF56)
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)
Gene: FBXL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.757

Property	Details
Experiments	30190310
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	BTB~LRR_6
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 601 Hs			1 701
+	Hs
		1262088 KBTB7_HUMAN (10-598): 1.43e-161: 479: 27.66		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1201316 KBTB6_HUMAN (11-598): 3.2e-159: 473: 27.39		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1121505 KLH26_HUMAN (10-588): 1.15e-142: 428: 22.31		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1350481 KLH13_HUMAN (1-588): 8.95e-142: 427: 21.57		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354637 KLHL3_HUMAN (2-586): 5.29e-142: 426: 22.59		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1049349 KEAP1_HUMAN (1-586): 2.25e-139: 420: 21.23		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1327770 KLH25_HUMAN (1-582): 4.41e-121: 372: 23.64		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354639 KLH21_HUMAN (12-510): 1.45e-45: 172: 26.03		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		152501 ENC1_HUMAN (31-578): 3.15e-45: 171: 26.26		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1221252 KLHL7_HUMAN (39-516): 1.5e-44: 169: 25.05		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354646 IPP_HUMAN (198-479): 2.21e-37: 148: 17.29		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		307226 KLHL2_HUMAN (388-600): 1.72e-37: 148: 20.00		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1348054 KLH28_HUMAN (125-479): 7.35e-36: 143: 15.87		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1120825 KLH12_HUMAN (266-442): 5.66e-27: 117: 20.90		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354642 KLH20_HUMAN (250-440): 5.47e-24: 108: 16.23		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1350369 KLHL9_HUMAN (438-597): 6.16e-22: 102: 15.85		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1164601 KLH17_HUMAN (227-440): 9.47e-22: 101: 16.36		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1153798 KLH10_HUMAN (203-441): 5.27e-21: 99.1: 11.30		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1164633 KLH24_HUMAN (375-594): 9.91e-21: 98.4: 14.78		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1239687 KLH23_HUMAN (443-594): 1e-16: 85.7: 14.91		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00