HitPredict

Interactor 1: PJA1 (Q8NG27)
E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 2.3.2.27) (RING finger protein 70) (RING-type E3 ubiquitin transferase Praja-1)
Gene: PJA1

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	28514442, 33961781, 22626734
Identification Methods	affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 1102
+	Hs
		1273976 RNF6_HUMAN (1-640): 5.26e-52: 192: 14.82		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273840 RN126_HUMAN (545-639): 9.16e-30: 121: 40.00		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1245282 PJA1_HUMAN (1-643): 1.23e-161: 480: 100.00		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08
+	Hs
		1245314 PJA1_HUMAN (1-643): 1.23e-161: 480: 100.00		UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13
+	Hs
		1174024 PJA1_HUMAN (1-643): 1.23e-161: 480: 100.00		UBP51_HUMAN (61-525): 3.06e-95: 321: 16.58
+	Hs
		196293 PJA2_HUMAN (1-642): 1.14e-129: 399: 44.94		UBP46_HUMAN (204-522): 1.27e-91: 299: 25.50
+	Hs
		1273768 RNF6_HUMAN (1-640): 5.26e-52: 192: 14.82		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08
+	Hs
		1273774 RN115_HUMAN (432-639): 6.28e-33: 130: 21.88		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08