HitPredict

Interactor 1: PJA1 (Q8NG27)
E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 2.3.2.27) (RING finger protein 70) (RING-type E3 ubiquitin transferase Praja-1)
Gene: PJA1

Interactor 2: UBP28 (Q96RU2)
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)
Gene: USP28

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	22626734
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 1077
+	Hs
		865076 TTC3_HUMAN (29-635): 4.22e-87: 299: 12.34		UBP28_HUMAN (1-1077): 0: 1069: 100.00
+	Hs
		800601 PJA1_HUMAN (1-643): 1.23e-161: 480: 100.00		UBP5_HUMAN (28-649): 4.98e-77: 273: 12.71
+	Hs
		1245282 PJA1_HUMAN (1-643): 1.23e-161: 480: 100.00		USP9X_HUMAN (136-452): 1.14e-61: 233: 18.33
+	Hs
		1174024 PJA1_HUMAN (1-643): 1.23e-161: 480: 100.00		UBP51_HUMAN (158-414): 1.36e-62: 228: 18.77
+	Hs
		196293 PJA2_HUMAN (1-642): 1.14e-129: 399: 44.94		UBP46_HUMAN (158-406): 1.63e-64: 224: 20.36
+	Hs
		1245283 PJA1_HUMAN (1-643): 1.23e-161: 480: 100.00		UBP7_HUMAN (547-839): 8.01e-23: 107: 20.13
+	Hs
		1245314 PJA1_HUMAN (1-643): 1.23e-161: 480: 100.00		UBP36_HUMAN (473-649): 5.03e-09: 62.7: 17.98
+	Hs
		1273768 RNF6_HUMAN (1-640): 5.26e-52: 192: 14.82		USP9X_HUMAN (136-452): 1.14e-61: 233: 18.33
+	Hs
		1273774 RN115_HUMAN (432-639): 6.28e-33: 130: 21.88		USP9X_HUMAN (136-452): 1.14e-61: 233: 18.33
+	Hs
		1273976 RNF6_HUMAN (1-640): 5.26e-52: 192: 14.82		UBP7_HUMAN (547-839): 8.01e-23: 107: 20.13
+	Hs
		1273840 RN126_HUMAN (545-639): 9.16e-30: 121: 40.00		UBP7_HUMAN (547-839): 8.01e-23: 107: 20.13
+	Hs
		271177 RN126_HUMAN (545-639): 9.16e-30: 121: 40.00		UBP2_HUMAN (434-653): 1.59e-15: 83.1: 17.86