HitPredict

Interactor 1: PJA1 (Q8NG27)
E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 2.3.2.27) (RING finger protein 70) (RING-type E3 ubiquitin transferase Praja-1)
Gene: PJA1

Interactor 2: SMC6 (Q96SB8)
Structural maintenance of chromosomes protein 6 (SMC protein 6) (SMC-6) (hSMC6)
Gene: SMC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	30185588, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 1091
+	Hs
		1221582 PJA1_HUMAN (1-643): 1.23e-161: 480: 100.00		SMC5_HUMAN (5-1069): 1.28e-69: 255: 16.18
+	Hs
		865077 TTC3_HUMAN (29-635): 4.22e-87: 299: 12.34		SMC6_HUMAN (1-1091): 2.11e-115: 385: 100.00
+	Hs
		551641 TTC3_HUMAN (29-635): 4.22e-87: 299: 12.34		DESP_HUMAN (126-744): 7.41e-23: 108: 8.27
+	Hs
		1313518 RN126_HUMAN (545-639): 9.16e-30: 121: 40.00		SMC3_HUMAN (127-1042): 1.13e-48: 191: 12.77
+	Hs
		282514 RNF8_HUMAN (383-639): 1.07e-34: 139: 16.85		DESP_HUMAN (126-744): 7.41e-23: 108: 8.27