HitPredict

Interactor 1: MFSD8 (Q8NHS3)
Major facilitator superfamily domain-containing protein 8 (Ceroid-lipofuscinosis neuronal protein 7)
Gene: MFSD8

Interactor 2: P2Y12 (Q9H244)
P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999)
Gene: P2RY12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 518 Hs			1 342
+	Hs
		849687 MFSD8_HUMAN (1-518): 1.42e-132: 396: 100.00		CCR6_HUMAN (16-314): 3.66e-89: 273: 22.88
+	Hs
		895680 MFSD8_HUMAN (1-518): 1.42e-132: 396: 100.00		CXCR4_HUMAN (18-330): 1.17e-71: 228: 22.54
+	Hs
		666332 MFSD8_HUMAN (1-518): 1.42e-132: 396: 100.00		NK3R_HUMAN (8-342): 1.51e-65: 215: 19.36
+	Hs
		781088 MFSD8_HUMAN (1-518): 1.42e-132: 396: 100.00		OPRX_HUMAN (13-330): 8.68e-64: 208: 21.56
+	Hs
		1031020 MFSD8_HUMAN (1-518): 1.42e-132: 396: 100.00		GPR17_HUMAN (6-333): 1.6e-63: 207: 24.01
+	Hs
		783827 SVOP_HUMAN (22-497): 1.47e-62: 215: 14.92		CCR2_HUMAN (22-322): 3.34e-64: 209: 22.85
+	Hs
		723350 MFSD9_HUMAN (37-504): 5.47e-42: 158: 14.32		APJ_HUMAN (1-340): 9.92e-70: 224: 22.16
+	Hs
		429078 SV2A_HUMAN (11-516): 1.99e-34: 139: 12.55		ADRB2_HUMAN (4-337): 2.52e-67: 219: 16.44
+	Hs
		1234017 SVOP_HUMAN (22-497): 1.47e-62: 215: 14.92		CLTR2_HUMAN (6-314): 3.29e-27: 111: 29.26
+	Hs
		876117 MFS10_HUMAN (70-490): 5.42e-38: 146: 16.25		PAR2_HUMAN (22-315): 3.79e-25: 106: 26.42