Interactor 1: TPC2 (Q8NHX9)
Two pore channel protein 2 (Two pore calcium channel protein 2)
Gene: TPCN2

Interactor 2: TPC1 (Q9ULQ1)
Two pore channel protein 1 (Two pore calcium channel protein 1) (Voltage-dependent calcium channel protein TPC1)
Gene: TPCN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 21903581
Identification Methods anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~Ion_trans
Common GO terms GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0010008 - endosome membrane
GO:0015280 - ligand-gated sodium channel activity
GO:0034220 - monoatomic ion transmembrane transport
and 5 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 752
Hs

1 816
+ Hs
+ Mm
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+ At
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024