HitPredict

Interactor 1: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1

Interactor 2: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.922

The method score is based on:

Property Details
Experiments 12615916, 37689310, 16931761, 21135113, 23289756
Identification Methods affinity chromatography technology, proximity labelling technology, enzymatic study, protein complementation assay
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains WD40~WD40, zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0010212 - response to ionizing radiation
GO:0016567 - protein ubiquitination
and 6 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 731
Hs

1 731
+ At
+ At
+ At
+ At
+ Hs
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024