HitPredict

Interactor 1: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 731 Hs			1 2514
+	Hs
		1346974 NLE1_HUMAN (582-729): 3.62e-35: 141: 15.33		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		1083443 RBBP7_HUMAN (476-629): 3.89e-12: 70.9: 29.34		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		1246204 COP1_HUMAN (1-731): 0: 540: 100.00		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		261563 SNR40_HUMAN (307-447): 5.3e-10: 63.7: 12.67		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		1281467 FBXW7_HUMAN (452-730): 4.46e-69: 242: 17.15		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		793042 LIS1_HUMAN (509-730): 2.11e-55: 197: 21.24		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		1281391 FBXW7_HUMAN (452-730): 4.46e-69: 242: 17.15		PRR36_HUMAN (2-1025): 1.03e-10: 69.6: 8.95
+	Hs
		1346970 NLE1_HUMAN (582-729): 3.62e-35: 141: 15.33		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		1302927 NLE1_HUMAN (582-729): 3.62e-35: 141: 15.33		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		1074805 TAF5_HUMAN (525-731): 1.71e-35: 146: 17.79		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		997958 RBBP4_HUMAN (512-702): 3.22e-20: 96: 14.49		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		1288394 SNR40_HUMAN (307-447): 5.3e-10: 63.7: 12.67		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		997865 RBBP4_HUMAN (512-702): 3.22e-20: 96: 14.49		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		903450 WDR5_HUMAN (632-730): 5.38e-16: 81.8: 18.18		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		997967 RBBP4_HUMAN (512-702): 3.22e-20: 96: 14.49		CABIN_HUMAN (722-1134): 2.25e-13: 78.9: 19.17
+	Hs
		1083357 RBBP7_HUMAN (476-629): 3.89e-12: 70.9: 29.34		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		903374 WDR5_HUMAN (632-730): 5.38e-16: 81.8: 18.18		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		1083355 RBBP7_HUMAN (476-629): 3.89e-12: 70.9: 29.34		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		1288258 SNR40_HUMAN (307-447): 5.3e-10: 63.7: 12.67		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		1264784 SNR40_HUMAN (307-447): 5.3e-10: 63.7: 12.67		TITIN_HUMAN (1125-2056): 5.55e-11: 70.9: 8.61