HitPredict

Interactor 1: INADL (Q8NI35)
InaD-like protein (Inadl protein) (hINADL) (Channel-interacting PDZ domain-containing protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions)
Gene: PATJ

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	L27~L27_2, PDZ~PDZ
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1801 Hs			1 197
+	Hs
		1246435 INADL_HUMAN (1-1801): 0: 1090: 100.00		LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69
+	Hs
		158295 INADL_HUMAN (1-1801): 0: 1090: 100.00		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		1246409 INADL_HUMAN (1-1801): 0: 1090: 100.00		INADL_HUMAN (112-194): 6.16e-11: 62.8: 30.12
+	Hs
		1246425 INADL_HUMAN (1-1801): 0: 1090: 100.00		MAGI1_HUMAN (94-172): 5.41e-10: 60.1: 35.44
+	Hs
		280082 MPDZ_HUMAN (1494-1800): 2.48e-27: 124: 20.19		LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00
+	Hs
		280072 MPDZ_HUMAN (1494-1800): 2.48e-27: 124: 20.19		LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69
+	Hs
		158256 MPDZ_HUMAN (1494-1800): 2.48e-27: 124: 20.19		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		158277 DLG1_HUMAN (565-1029): 2.84e-24: 113: 16.95		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		159249 DLG3_HUMAN (544-989): 6.06e-32: 137: 15.16		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		1077285 DLG3_HUMAN (544-989): 6.06e-32: 137: 15.16		DLG2_HUMAN (23-196): 1.68e-25: 104: 23.63
+	Mm
		936188 DLG3_MOUSE (544-976): 3.73e-30: 132: 15.25		DLG2_MOUSE (23-196): 1.12e-25: 105: 23.63
+	Mm
		1119795 Q52KF7_MOUSE (544-989): 8.28e-32: 137: 14.95		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		942364 DLG3_HUMAN (544-989): 6.06e-32: 137: 15.16		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Hs
		1021542 DLG3_HUMAN (544-989): 6.06e-32: 137: 15.16		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		159200 DLG1_HUMAN (565-1029): 2.84e-24: 113: 16.95		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Mm
		936180 DLG3_MOUSE (544-976): 3.73e-30: 132: 15.25		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Rn
		677790 DLG3_RAT (544-976): 4.07e-30: 132: 15.25		DLG4_RAT (59-195): 2.17e-23: 98.7: 26.76
+	Rn
		1144010 DLG3_RAT (544-976): 4.07e-30: 132: 15.25		DLG1_RAT (94-178): 2.77e-21: 92.5: 37.78
+	Mm
		1113136 Q3UP61_MOUSE (565-989): 4.01e-25: 115: 17.15		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		1021482 DLG1_HUMAN (565-1029): 2.84e-24: 113: 16.95		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60