HitPredict

Interactor 1: RAB38 (Q8QZZ8)
Ras-related protein Rab-38
Gene: RAB38

Interactor 2: RAF1 (Q99N57)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26885862
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	C1_1~Ras, Pkinase~Ras, RBD~Ras
Common GO terms	GO:0005739 - mitochondrion GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 211 Mm			1 648
+	Hs
		373978 RAB10_HUMAN (1-208): 7.41e-84: 248: 36.97		RAF1_HUMAN (1-648): 0: 717: 97.69
+	Hs
		373973 RAB8A_HUMAN (3-206): 5.64e-80: 239: 32.52		RAF1_HUMAN (1-648): 0: 717: 97.69
+	Hs
		374007 RAB1A_HUMAN (1-209): 1.59e-79: 238: 31.13		RAF1_HUMAN (1-648): 0: 717: 97.69
+	Hs
		374854 RAB1B_HUMAN (4-209): 4.55e-78: 234: 31.07		RAF1_HUMAN (1-648): 0: 717: 97.69
+	Hs
		373960 RAB38_HUMAN (1-211): 2.7e-73: 222: 97.16		RAF1_HUMAN (1-648): 0: 717: 97.69
+	Hs
		373902 RAB7A_HUMAN (3-184): 3.31e-35: 125: 36.07		RAF1_HUMAN (1-648): 0: 717: 97.69
+	Hs
		542851 RAB1A_HUMAN (1-209): 1.59e-79: 238: 31.13		BRAF_HUMAN (40-647): 0: 596: 55.95
+	Mm
		655971 RAB38_MOUSE (1-211): 2.91e-73: 222: 100.00		BRAF_MOUSE (2-647): 0: 591: 52.54
+	Mm
		384066 RAB38_MOUSE (1-211): 2.91e-73: 222: 100.00		ARAF_MOUSE (47-646): 0: 553: 59.93
+	Hs
		433358 RAB35_HUMAN (5-205): 3.95e-83: 247: 36.10		YES_HUMAN (329-607): 3.61e-105: 331: 33.57
+	Hs
		523004 RB11B_HUMAN (2-211): 3.62e-73: 222: 27.15		SRC_HUMAN (331-607): 3.97e-106: 333: 33.10