HitPredict

Interactor 1: EIF3F (O00303)
Eukaryotic translation initiation factor 3 subunit F (eIF3f) (Deubiquitinating enzyme eIF3f) (EC 3.4.19.12) (Eukaryotic translation initiation factor 3 subunit 5) (eIF-3-epsilon) (eIF3 p47)
Gene: EIF3F

Interactor 2: EIF3H (O15372)
Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3-gamma) (eIF3 p40 subunit)
Gene: EIF3H

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 32269044, 24981860, 19615732, 26186194, 28514442, 31527668, 33961781, 35235311, 18599441, 23623729
Identification Methods affinity chromatography technology, cross-linking study, mass spectrometry studies of complexes, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~eIF3h_C, JAB~JAB, MitMem_reg~eIF3h_C, JAB~MitMem_reg
Common GO terms GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005852 - eukaryotic translation initiation factor 3 complex
GO:0006413 - translational initiation
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 357
Hs

1 352
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Mm
+ Hs
+ Hs
+ At
+ At
+ At
+ Hs
+ Dm
+ At
+ At
+ Hs
+ Sp
+ Ce
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024