HitPredict

Interactor 1: RORB (Q8R1B8)
Nuclear receptor ROR-beta (Nuclear receptor RZR-beta) (Nuclear receptor subfamily 1 group F member 2) (Retinoid-related orphan receptor-beta)
Gene: RORB

Interactor 2: Q8VD35 (Q8VD35)
Orthodenticle homeobox 2 (Otx2 protein)
Gene: Otx2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26426291
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 470 Mm			1 289
+	Hs
		197676 NR2C2_HUMAN (8-458): 7.91e-101: 315: 20.33		CRX_HUMAN (1-289): 5.69e-41: 145: 46.91
+	Hs
		620133 NR2C2_HUMAN (8-458): 7.91e-101: 315: 20.33		PAX7_HUMAN (6-255): 7.52e-35: 133: 25.10
+	Hs
		641339 NR2C2_HUMAN (8-458): 7.91e-101: 315: 20.33		PAX6_HUMAN (5-250): 1.42e-34: 131: 24.39
+	Hs
		824492 NR2C2_HUMAN (8-458): 7.91e-101: 315: 20.33		LHX3_HUMAN (39-264): 6.99e-35: 131: 21.46
+	Dm
		52977 A1Z858_DROME (10-467): 1.87e-94: 301: 38.36		Q9XZC2_DROME (5-254): 2.61e-33: 129: 21.46
+	Hs
		197656 NR2C1_HUMAN (9-458): 3.12e-87: 280: 20.70		CRX_HUMAN (1-289): 5.69e-41: 145: 46.91
+	Hs
		525279 NR2C1_HUMAN (9-458): 3.12e-87: 280: 20.70		PAX7_HUMAN (6-255): 7.52e-35: 133: 25.10
+	Mm
		703483 STF1_MOUSE (14-458): 1.94e-89: 282: 21.77		PITX1_MOUSE (14-259): 5.43e-35: 130: 27.02
+	Hs
		525281 NR2C1_HUMAN (9-458): 3.12e-87: 280: 20.70		PAX6_HUMAN (5-250): 1.42e-34: 131: 24.39
+	Hs
		525335 NR2C1_HUMAN (9-458): 3.12e-87: 280: 20.70		LHX3_HUMAN (39-264): 6.99e-35: 131: 21.46
+	Hs
		197862 NR2E3_HUMAN (11-461): 1.72e-81: 259: 20.13		CRX_HUMAN (1-289): 5.69e-41: 145: 46.91
+	Mm
		222325 NR2E3_MOUSE (11-461): 4.88e-79: 252: 19.82		CRX_MOUSE (1-289): 8.79e-41: 145: 45.93
+	Hs
		941900 STF1_HUMAN (14-458): 1.17e-79: 256: 20.04		PITX1_HUMAN (16-259): 8.79e-35: 129: 26.42
+	Hs
		487977 RARA_HUMAN (20-95): 1e-42: 159: 61.84		ALX1_HUMAN (2-197): 2.59e-37: 136: 28.14
+	Dm
		558466 7UP1_DROME (19-100): 5.4e-27: 115: 59.76		Q9XZU0_DROME (30-281): 1.02e-37: 138: 23.93
+	Dm
		558443 7UP1_DROME (19-100): 5.4e-27: 115: 59.76		Q8T0V5_DROME (30-281): 1.94e-37: 137: 23.93
+	Dm
		185923 E75BB_DROME (207-449): 1.4e-24: 109: 30.23		PITX_DROME (14-256): 2.49e-33: 129: 22.54
+	Dm
		569138 E75BC_DROME (207-449): 7.92e-25: 110: 30.23		HMOC_DROME (36-94): 2.28e-27: 112: 98.31
+	Dm
		525266 E75BB_DROME (207-449): 1.4e-24: 109: 30.23		HMOC_DROME (36-94): 2.28e-27: 112: 98.31