Interactor 1: NLRP3 (Q8R4B8)
NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Cold autoinflammatory syndrome 1 protein homolog) (Cryopyrin) (Mast cell maturation-associated-inducible protein 1) (PYRIN-containing APAF1-like protein 1)
Gene: NLRP3
Interactor 2: NLRP3 (Q8R4B8)
NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Cold autoinflammatory syndrome 1 protein homolog) (Cryopyrin) (Mast cell maturation-associated-inducible protein 1) (PYRIN-containing APAF1-like protein 1)
Gene: NLRP3
Species: Mus musculus
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.618 |
The method score is based on:
Property | Details |
---|---|
Experiments | 27993998 |
Identification Methods | cross-linking study |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | LRR_6~LRR_6, NACHT~NACHT, NACHT~NLRC4_HD2, NACHT~NOD2_WH, NLRC4_HD2~NOD2_WH, PYRIN~PYRIN |
Common GO terms | GO:0000139 - Golgi membrane GO:0002221 - pattern recognition receptor signaling pathway GO:0002523 - leukocyte migration involved in inflammatory response GO:0002526 - acute inflammatory response GO:0002674 - negative regulation of acute inflammatory response and 48 others more... |
Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024