HitPredict

Interactor 1: IFIH1 (Q8R5F7)
Interferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13) (Helicase with 2 CARD domains) (Helicard) (Interferon induced with helicase C domain protein 1) (Melanoma differentiation-associated protein 5) (MDA-5) (RIG-I-like receptor 2) (RLR-2)
Gene: IFIH1

Interactor 2: IFIH1 (Q8R5F7)
Interferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13) (Helicase with 2 CARD domains) (Helicard) (Interferon induced with helicase C domain protein 1) (Melanoma differentiation-associated protein 5) (MDA-5) (RIG-I-like receptor 2) (RLR-2)
Gene: IFIH1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.584

The method score is based on:

Property Details
Experiments 23090998
Identification Methods transmission electron microscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CARD_2~CARD_2, CARD_2~ResIII, CARD_2~RIG-I_C, Helicase_C~Helicase_C, Helicase_C~ResIII, Helicase_C~RIG-I_C, Helicase_C~RIG-I_C-RD, ResIII~ResIII, RIG-I_C~ResIII, RIG-I_C-RD~ResIII, RIG-I_C~RIG-I_C, RIG-I_C~RIG-I_C-RD, RIG-I_C-RD~RIG-I_C-RD
Common GO terms GO:0003677 - DNA binding
GO:0003724 - RNA helicase activity
GO:0003725 - double-stranded RNA binding
GO:0003727 - single-stranded RNA binding
GO:0005524 - ATP binding
and 24 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1025
Mm

1 1025
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ At
+ Hs
+ Hs
+ At
+ Hs
+ Ce
+ Mm
+ At
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024