HitPredict

Interactor 1: WASF1 (Q8R5H6)
Actin-binding protein WASF1 (Protein WAVE-1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1)
Gene: WASF1

Interactor 2: TSC1 (Q9EP53)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030027 - lamellipodium
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 559 Mm			1 1161
+	Hs
		999157 EP300_HUMAN (78-554): 1.13e-28: 123: 15.74		CACO1_HUMAN (662-1080): 1.45e-42: 168: 15.86
+	Hs
		724792 EP300_HUMAN (78-554): 1.13e-28: 123: 15.74		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		254474 EP300_HUMAN (78-554): 1.13e-28: 123: 15.74		ROCK2_HUMAN (398-1090): 3.16e-25: 116: 12.76
+	Hs
		724946 CBP_HUMAN (82-551): 1.55e-25: 113: 12.26		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Mm
		222882 ACK1_MOUSE (251-500): 6.41e-20: 96.2: 21.01		MY18A_MOUSE (540-1147): 1.87e-24: 113: 10.97
+	Hs
		998727 EP300_HUMAN (78-554): 1.13e-28: 123: 15.74		EEA1_HUMAN (408-851): 3.09e-13: 76.8: 8.35
+	Hs
		149330 SC31B_HUMAN (219-523): 8.76e-11: 67: 16.03		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		149481 PCLO_HUMAN (177-528): 8.17e-10: 64.3: 15.75		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		725147 EP300_HUMAN (78-554): 1.13e-28: 123: 15.74		MYH10_HUMAN (617-910): 9.54e-10: 65.3: 13.27
+	Mm
		222845 ACK1_MOUSE (251-500): 6.41e-20: 96.2: 21.01		MYH10_MOUSE (708-1000): 6.45e-15: 82.3: 14.77
+	Mm
		222875 ACK1_MOUSE (251-500): 6.41e-20: 96.2: 21.01		MYH9_MOUSE (773-1161): 3.4e-11: 70.2: 11.72