HitPredict

Interactor 1: M2K5 (Q8RXG3)
Mitogen-activated protein kinase kinase 5 (AtMAP2Kalpha) (AtMEK5) (AtMKK5) (MAP kinase kinase 5) (EC 2.7.12.2)
Gene: MKK5

Interactor 2: GPLPB (Q9C4Z6)
Small ribosomal subunit protein RACK1y (Guanine nucleotide-binding protein subunit beta-like protein B) (Receptor for activated C kinase 1B)
Gene: RACK1B

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	25731164
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 348 At			1 326
+	At
		285315 M2K4_ARATH (1-337): 1.32e-128: 374: 78.04		GPLPC_ARATH (1-326): 1.22e-103: 308: 92.95
+	At
		1247452 M2K5_ARATH (1-348): 5.24e-128: 372: 100.00		GPLPC_ARATH (1-326): 1.22e-103: 308: 92.95
+	At
		285312 M2K4_ARATH (1-337): 1.32e-128: 374: 78.04		GPLPB_ARATH (1-326): 7.38e-103: 306: 100.00
+	At
		188954 M2K4_ARATH (1-337): 1.32e-128: 374: 78.04		GBLPA_ARATH (1-326): 5.78e-100: 298: 87.46
+	At
		189057 M2K5_ARATH (1-348): 5.24e-128: 372: 100.00		GBLPA_ARATH (1-326): 5.78e-100: 298: 87.46
+	At
		189107 M2K9_ARATH (35-326): 2.58e-114: 335: 51.34		GBLPA_ARATH (1-326): 5.78e-100: 298: 87.46
+	Mm
		554925 KPCE_MOUSE (5-346): 6.13e-123: 372: 19.61		FBXW7_MOUSE (133-325): 2.14e-38: 146: 20.00
+	Hs
		681967 AKT1_HUMAN (44-347): 1.93e-124: 367: 23.03		FBXW7_HUMAN (133-325): 5.76e-38: 144: 20.00
+	Dm
		186204 AKT1_DROME (26-347): 3.24e-124: 371: 20.96		GBLP_DROME (136-325): 3.88e-33: 126: 23.00
+	Hs
		1027412 STK3_HUMAN (47-338): 2.86e-113: 339: 31.33		FBXW7_HUMAN (133-325): 5.76e-38: 144: 20.00
+	Hs
		160697 AURKA_HUMAN (3-333): 2.03e-113: 337: 27.54		FBXW7_HUMAN (133-325): 5.76e-38: 144: 20.00
+	Hs
		625543 CDK2_HUMAN (67-335): 1.48e-111: 328: 29.93		FBXW7_HUMAN (133-325): 5.76e-38: 144: 20.00
+	Hs
		929405 KPCE_HUMAN (5-346): 6.13e-123: 372: 19.61		RACK1_HUMAN (12-138): 3.83e-15: 76.6: 16.38
+	Hs
		625337 CDK2_HUMAN (67-335): 1.48e-111: 328: 29.93		RACK1_HUMAN (12-138): 3.83e-15: 76.6: 16.38
+	Hs
		734902 MP2K2_HUMAN (69-328): 2.24e-40: 148: 32.69		WDR5_HUMAN (46-325): 1.83e-80: 249: 26.15
+	Hs
		625202 CDK2_HUMAN (67-335): 1.48e-111: 328: 29.93		LIS1_HUMAN (233-326): 4.17e-11: 65.4: 16.84
+	Hs
		972235 MP2K1_HUMAN (69-328): 2.23e-45: 161: 34.10		FBXW7_HUMAN (133-325): 5.76e-38: 144: 20.00
+	Hs
		929406 MP2K1_HUMAN (69-328): 2.23e-45: 161: 34.10		RACK1_HUMAN (12-138): 3.83e-15: 76.6: 16.38
+	Hs
		929752 M3K4_HUMAN (71-325): 4.53e-39: 149: 35.88		RACK1_HUMAN (12-138): 3.83e-15: 76.6: 16.38
+	Hs
		734909 MP2K2_HUMAN (69-328): 2.24e-40: 148: 32.69		RACK1_HUMAN (12-138): 3.83e-15: 76.6: 16.38