HitPredict

Interactor 1: EIF3F (O00303)
Eukaryotic translation initiation factor 3 subunit F (eIF3f) (Deubiquitinating enzyme eIF3f) (EC 3.4.19.12) (Eukaryotic translation initiation factor 3 subunit 5) (eIF-3-epsilon) (eIF3 p47)
Gene: EIF3F

Interactor 2: EF1A1 (P68104)
Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene: EEF1A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	16169070, 31527668
Identification Methods	two hybrid, affinity chromatography technology, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 357 Hs			1 462
+	Hs
		984377 CSN6_HUMAN (76-357): 3.14e-101: 303: 22.73		EF1A2_HUMAN (1-461): 0: 567: 92.63
+	Hs
		124751 EIF3F_HUMAN (1-357): 2.36e-122: 358: 100.00		ERF3A_HUMAN (2-443): 3.59e-162: 469: 37.47
+	Hs
		176996 EIF3H_HUMAN (84-353): 3.84e-76: 240: 16.17		EF1A1_HUMAN (1-462): 0: 578: 100.00
+	Hs
		130843 PSDE_HUMAN (81-356): 5.98e-69: 220: 15.31		EF1A1_HUMAN (1-462): 0: 578: 100.00
+	Sc
		368469 RPN8_YEAST (90-356): 9.68e-83: 256: 26.21		EF1A_YEAST (1-445): 0: 538: 80.90
+	Hs
		130859 PSDE_HUMAN (81-356): 5.98e-69: 220: 15.31		EF1A2_HUMAN (1-461): 0: 567: 92.63
+	Hs
		176936 EIF3H_HUMAN (84-353): 3.84e-76: 240: 16.17		ERF3A_HUMAN (2-443): 3.59e-162: 469: 37.47