Interactor 1: PHO (Q8ST83)
Polycomb protein PHO (Protein pleiohomeotic) (Transcription factor YY1 homolog)
Gene: PHO

Interactor 2: SMBT (Q9VK33)
Polycomb protein Sfmbt (Scm-like with four MBT domain-containing protein 1) (dSfmbt)
Gene: Sfmbt

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.725

The method score is based on:

Property Details
Experiments 21415365, 24186981, 16618800, 29208012, 36070387
Identification Methods affinity chromatography technology, x-ray crystallography, pull down, anti tag coimmunoprecipitation, cosedimentation through density gradient, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0010629 - negative regulation of gene expression
GO:0031507 - heterochromatin formation
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 520
Dm

1 1220
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024