HitPredict

Interactor 1: HIPPO (Q8T0S6)
Serine/threonine-protein kinase hippo (EC 2.7.11.1) (Drosophila homolog of MST1 and MST2) (STE20-like kinase MST) (dMST)
Gene: hpo

Interactor 2: WARTS (Q9VA38)
Serine/threonine-protein kinase Warts (EC 2.7.11.1)
Gene: wts

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 14561774, 16906135, 14502295, 19733165, 26403189, 12941273, 24012335, 26364751
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0007298 - border follicle cell migration
GO:0007406 - negative regulation of neuroblast proliferation
and 11 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 669
Dm

1 1105
+ Dm
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+ Mm
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Last updated: 15 Jul 2024