HitPredict

Interactor 1: HIPPO (Q8T0S6)
Serine/threonine-protein kinase hippo (EC 2.7.11.1) (Drosophila homolog of MST1 and MST2) (STE20-like kinase MST) (dMST)
Gene: hpo

Interactor 2: SAV (Q9VCR6)
Scaffold protein salvador (Shar-pei)
Gene: SAV

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.768

The method score is based on:

Property Details
Experiments 24012335, 20797625, 24114784, 26117838, 12941273, 12941274, 14502294, 14561774, 17174922, 22215676, 23263283, 23940457, 14502295, 20159598, 29519817, 26125558, 32117966, 32213597, 25484297, 22069188 and 4 others

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Identification Methods affinity chromatography technology, two hybrid, x-ray crystallography, pull down, enzymatic study, anti tag coimmunoprecipitation, experimental interaction detection
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0008285 - negative regulation of cell population proliferation
GO:0010212 - response to ionizing radiation
GO:0035329 - hippo signaling
GO:0043065 - positive regulation of apoptotic process
and 4 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 669
Dm

1 608
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Last updated: 15 Jul 2024