HitPredict

Interactor 1: HIPPO (Q8T0S6)
Serine/threonine-protein kinase hippo (EC 2.7.11.1) (Drosophila homolog of MST1 and MST2) (STE20-like kinase MST) (dMST)
Gene: hpo

Interactor 2: Q9W5E8 (Q9W5E8)
Uncharacterized protein, isoform A (Uncharacterized protein, isoform E)
Gene: spdi

Species: Drosophila melanogaster

Source: dip

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.50	0.464

Property	Details
Experiments	15710747
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 669 Dm			1 950
+	Hs
		568730 KAPCA_HUMAN (6-346): 3.17e-130: 389: 21.94		MILK1_HUMAN (846-948): 1.28e-35: 148: 45.19
+	Hs
		681696 AKT1_HUMAN (13-360): 6.81e-132: 398: 20.06		MYH9_HUMAN (200-863): 2.5e-27: 122: 12.69
+	Hs
		568568 KAPCA_HUMAN (6-346): 3.17e-130: 389: 21.94		MYH10_HUMAN (1-766): 3.49e-29: 128: 10.71
+	Hs
		568567 KAPCA_HUMAN (6-346): 3.17e-130: 389: 21.94		MYH9_HUMAN (200-863): 2.5e-27: 122: 12.69
+	Hs
		725152 PAK2_HUMAN (26-317): 5.83e-118: 364: 37.08		MYH10_HUMAN (1-766): 3.49e-29: 128: 10.71
+	Hs
		129044 PLK4_HUMAN (40-641): 1.11e-128: 405: 19.44		CP250_HUMAN (2-748): 1.02e-15: 84.5: 8.77
+	Hs
		129013 PLK4_HUMAN (40-641): 1.11e-128: 405: 19.44		MRCKA_HUMAN (38-423): 1.26e-14: 80.8: 13.38
+	Hs
		610795 KAPCB_HUMAN (6-342): 3.49e-129: 387: 21.90		MYH2_HUMAN (1-515): 1.27e-18: 94.1: 9.37
+	Hs
		681881 AKT1_HUMAN (13-360): 6.81e-132: 398: 20.06		GRDN_HUMAN (326-904): 7.23e-14: 78.3: 10.31
+	Hs
		610802 KAPCB_HUMAN (6-342): 3.49e-129: 387: 21.90		MYH4_HUMAN (382-889): 9.4e-16: 84.5: 10.43
+	Hs
		568689 KAPCA_HUMAN (6-346): 3.17e-130: 389: 21.94		GRDN_HUMAN (326-904): 7.23e-14: 78.3: 10.31
+	Hs
		1344754 SNRK_HUMAN (41-412): 1.65e-115: 365: 24.68		MYH2_HUMAN (1-515): 1.27e-18: 94.1: 9.37
+	Hs
		528359 KAPCB_HUMAN (6-342): 3.49e-129: 387: 21.90		MYH6_HUMAN (1-393): 1.01e-11: 71.4: 11.71
+	Hs
		296412 STK10_HUMAN (22-486): 2.03e-116: 373: 32.71		CYTSB_HUMAN (75-473): 1.43e-10: 67.5: 12.35
+	Hs
		1023138 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		MYH13_HUMAN (6-863): 9.33e-32: 136: 9.89
+	Hs
		1023144 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		MYH15_HUMAN (1-795): 1.05e-27: 123: 9.83
+	Hs
		528408 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		MYH8_HUMAN (5-581): 3.01e-23: 109: 12.25
+	Hs
		1023137 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		MYH2_HUMAN (1-515): 1.27e-18: 94.1: 9.37
+	Hs
		528369 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		MYH6_HUMAN (1-393): 1.01e-11: 71.4: 11.71
+	Hs
		522609 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		MYH7_HUMAN (1-358): 8.59e-10: 65.2: 9.51