HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: ARI1A (O14497)
AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A) (B120) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A) (Osa homolog 1) (hOSA1) (SWI-like protein) (SWI/SNF complex protein p270) (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1) (hELD)
Gene: ARID1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	31048545, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 2285
+	Hs
		146268 ITCH_HUMAN (1-870): 0: 902: 54.26		ARI1A_HUMAN (11-2285): 0: 871: 100.00
+	Hs
		146175 NEDD4_HUMAN (90-867): 0: 731: 35.94		ARI1A_HUMAN (11-2285): 0: 871: 100.00
+	Hs
		125061 WWP2_HUMAN (1-870): 0: 982: 100.00		SC24D_HUMAN (390-714): 8.12e-15: 83: 20.06
+	Hs
		125588 WWP2_HUMAN (1-870): 0: 982: 100.00		ARI1B_HUMAN (515-1635): 3.77e-10: 68: 8.52
+	Hs
		125274 WWP2_HUMAN (1-870): 0: 982: 100.00		SC24C_HUMAN (61-366): 5.07e-10: 67.4: 16.15
+	Hs
		125687 WWP2_HUMAN (1-870): 0: 982: 100.00		DIDO1_HUMAN (355-972): 7.03e-09: 63.6: 12.24
+	Mm
		1208066 WWP2_MOUSE (1-870): 0: 971: 95.98		DIDO1_MOUSE (441-1007): 8.47e-09: 63.6: 13.23
+	Hs
		554367 WWP1_HUMAN (1-870): 0: 888: 58.38		MUC1_HUMAN (3-682): 2.67e-34: 146: 12.21
+	Hs
		1311993 WWP1_HUMAN (1-870): 0: 888: 58.38		DIDO1_HUMAN (355-972): 7.03e-09: 63.6: 12.24
+	Dm
		1374363 SUDX_DROME (14-870): 0: 852: 52.14		Q9VUH6_DROME (537-1217): 3.76e-09: 64.7: 12.48
+	Dm
		1370333 Q9VXR3_DROME (246-868): 6.38e-161: 523: 27.52		Q9VLS7_DROME (414-1494): 1.34e-13: 79.4: 11.70
+	Hs
		1350503 HECW2_HUMAN (154-531): 5.96e-16: 84.8: 17.23		MACF1_HUMAN (1693-1935): 6.32e-57: 222: 12.73
+	Hs
		1312007 HECW2_HUMAN (154-531): 5.96e-16: 84.8: 17.23		DIDO1_HUMAN (355-972): 7.03e-09: 63.6: 12.24