HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: WIPF1 (O43516)
WAS/WASL-interacting protein family member 1 (Protein PRPL-2) (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)
Gene: WIPF1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	25416956, 21516116
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 503
+	Hs
		125274 WWP2_HUMAN (1-870): 0: 982: 100.00		SC24C_HUMAN (53-484): 6.03e-11: 67.1: 17.51
+	Hs
		554367 WWP1_HUMAN (1-870): 0: 888: 58.38		MUC1_HUMAN (3-456): 2.41e-21: 100: 14.19
+	Dm
		1370333 Q9VXR3_DROME (246-868): 6.38e-161: 523: 27.52		Q9VLS7_DROME (22-498): 3.49e-09: 61.8: 11.41
+	Sc
		758550 TOM1_YEAST (494-869): 6.11e-158: 514: 40.26		SEC31_YEAST (207-503): 8.86e-09: 60.1: 15.56
+	Hs
		1264807 SMUF2_HUMAN (1-363): 5.89e-43: 169: 17.62		TITIN_HUMAN (144-368): 6.9e-11: 67.5: 18.33
+	Hs
		1170093 HECW2_HUMAN (154-531): 5.96e-16: 84.8: 17.23		SRCAP_HUMAN (2-497): 2.95e-09: 62.1: 12.65