HitPredict

Interactor 1: Q8T8V8 (Q8T8V8)
Proteasome subunit beta
Gene: Prosbeta5R1

Interactor 2: Q9VK14 (Q9VK14)
Proteasome subunit alpha type
Gene: Prosalpha6T

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 315 Dm			1 289
+	Dm
		522498 Q8T8V8_DROME (1-315): 5.68e-123: 356: 100.00		PSA1_DROME (1-237): 1.09e-97: 290: 63.90
+	Hs
		637323 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSA1_HUMAN (1-262): 7.51e-107: 312: 50.19
+	Hs
		637629 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSA2_HUMAN (1-236): 2.12e-101: 297: 29.41
+	Hs
		156228 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSA7_HUMAN (6-233): 9.24e-96: 284: 35.93
+	Hs
		638065 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSA4_HUMAN (1-232): 6.37e-94: 279: 28.87
+	Hs
		656051 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSA6_HUMAN (1-239): 4.74e-94: 279: 28.34
+	Hs
		637328 PSB5_HUMAN (1-275): 1.81e-90: 272: 46.18		PSA1_HUMAN (1-262): 7.51e-107: 312: 50.19
+	Dm
		522487 Q7K148_DROME (1-280): 2.97e-98: 292: 59.01		PSA1_DROME (1-237): 1.09e-97: 290: 63.90
+	Dm
		1178944 Q7K148_DROME (1-280): 2.97e-98: 292: 59.01		PSA5_DROME (1-236): 3.53e-94: 279: 28.57
+	Hs
		637634 PSB5_HUMAN (1-275): 1.81e-90: 272: 46.18		PSA2_HUMAN (1-236): 2.12e-101: 297: 29.41
+	Hs
		637325 PSA5_HUMAN (34-270): 9.93e-82: 249: 16.53		PSA1_HUMAN (1-262): 7.51e-107: 312: 50.19
+	Dm
		522528 Q9W470_DROME (13-306): 1.07e-88: 269: 24.10		PSA1_DROME (1-237): 1.09e-97: 290: 63.90
+	Hs
		156233 PSB5_HUMAN (1-275): 1.81e-90: 272: 46.18		PSA7_HUMAN (6-233): 9.24e-96: 284: 35.93
+	Sp
		145200 PSA5_SCHPO (34-275): 1.08e-84: 256: 17.32		PSA6_SCHPO (1-255): 1.06e-101: 299: 44.53
+	Hs
		656152 PSB5_HUMAN (1-275): 1.81e-90: 272: 46.18		PSA5_HUMAN (1-235): 9.39e-95: 281: 29.34
+	Hs
		638070 PSB5_HUMAN (1-275): 1.81e-90: 272: 46.18		PSA4_HUMAN (1-232): 6.37e-94: 279: 28.87
+	Hs
		656692 PSB5_HUMAN (1-275): 1.81e-90: 272: 46.18		PSA6_HUMAN (1-239): 4.74e-94: 279: 28.34
+	Hs
		637631 PSA5_HUMAN (34-270): 9.93e-82: 249: 16.53		PSA2_HUMAN (1-236): 2.12e-101: 297: 29.41
+	Hs
		156230 PSA5_HUMAN (34-270): 9.93e-82: 249: 16.53		PSA7_HUMAN (6-233): 9.24e-96: 284: 35.93
+	Hs
		638067 PSA5_HUMAN (34-270): 9.93e-82: 249: 16.53		PSA4_HUMAN (1-232): 6.37e-94: 279: 28.87