HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31048545
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 437
+	Hs
		125122 WWP2_HUMAN (1-870): 0: 982: 100.00		PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08
+	Hs
		125430 WWP2_HUMAN (1-870): 0: 982: 100.00		PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81
+	Hs
		516643 ITCH_HUMAN (1-870): 0: 902: 54.26		PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08
+	Hs
		125031 WWP2_HUMAN (1-870): 0: 982: 100.00		HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55
+	Sc
		376913 TOM1_YEAST (494-869): 6.11e-158: 514: 40.26		PABP_YEAST (2-281): 3.47e-29: 121: 12.15
+	Hs
		442513 SMUF1_HUMAN (1-385): 1.35e-45: 177: 17.77		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		442507 SMUF2_HUMAN (1-363): 5.89e-43: 169: 17.62		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		236084 SMUF1_HUMAN (1-385): 1.35e-45: 177: 17.77		HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55