HitPredict

Interactor 1: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Interactor 2: SMRC1 (Q92922)
SWI/SNF complex subunit SMARCC1 (BRG1-associated factor 155) (BAF155) (SWI/SNF complex 155 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1)
Gene: SMARCC1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.975

The method score is based on:

Property Details
Experiments 28514442, 24981860, 33961781, 19650111, 18809673, 20305087, 9584200, 35235311, 36652389, 16230384, 24421395
Identification Methods affinity chromatography technology, cross-linking study, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Myb_DNA-binding~Myb_DNA-binding, SWIRM~SWIRM, SWIRM-assoc_1~SWIRM-assoc_1, SWIRM-assoc_1~SWIRM-assoc_3, SWIRM-assoc_2~SWIRM-assoc_2
Common GO terms GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0003713 - transcription coactivator activity
GO:0005654 - nucleoplasm
GO:0006337 - nucleosome disassembly
and 21 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1214
Hs

1 1105
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024