HitPredict

Interactor 1: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Interactor 2: H2B1H (Q93079)
Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j)
Gene: H2BC9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1214 Hs			1 126
+	Hs
		1087279 SMRC2_HUMAN (1-1203): 0: 992: 100.00		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		707692 SMRC2_HUMAN (1-1203): 0: 992: 100.00		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		918539 SMRC2_HUMAN (1-1203): 0: 992: 100.00		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		1129833 SMRC1_HUMAN (4-1082): 0: 957: 60.83		H2B2F_HUMAN (1-126): 1.7e-55: 170: 99.21
+	Hs
		1087316 SMRC1_HUMAN (4-1082): 0: 957: 60.83		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		918577 SMRC1_HUMAN (4-1082): 0: 957: 60.83		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		886169 SMRC1_HUMAN (4-1082): 0: 957: 60.83		H2B1D_HUMAN (1-126): 3.03e-54: 167: 98.41
+	Hs
		1272926 SMRC1_HUMAN (4-1082): 0: 957: 60.83		H2B1L_HUMAN (1-126): 2.43e-53: 165: 97.62
+	Sc
		355924 RSC8_YEAST (336-751): 4.61e-104: 342: 28.30		H2B2_YEAST (3-125): 4.15e-41: 134: 71.55
+	Sc
		355528 RSC8_YEAST (336-751): 4.61e-104: 342: 28.30		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13
+	Sc
		355831 SWI3_YEAST (254-793): 1.23e-96: 329: 26.48		H2B2_YEAST (3-125): 4.15e-41: 134: 71.55
+	Sc
		355405 SWI3_YEAST (254-793): 1.23e-96: 329: 26.48		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13
+	Hs
		918433 MYSM1_HUMAN (276-523): 7.61e-53: 202: 22.96		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		1138815 MYSM1_HUMAN (276-523): 7.61e-53: 202: 22.96		H2B3B_HUMAN (1-126): 1.45e-52: 163: 96.03
+	Hs
		232191 KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		232398 KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		232087 KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		232076 KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00		H2B1D_HUMAN (1-126): 3.03e-54: 167: 98.41
+	Hs
		707690 KMT2C_HUMAN (650-1128): 8.15e-09: 62.4: 8.57		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		918533 KMT2C_HUMAN (650-1128): 8.15e-09: 62.4: 8.57		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21