HitPredict

Interactor 1: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12453419
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1214 Hs			1 1273
+	Hs
		1272922 SMRC1_HUMAN (4-1082): 0: 957: 60.83		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		232448 KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1302485 NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		261570 NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Mm
		1141044 NCOR1_MOUSE (597-1189): 5.86e-31: 135: 11.95		SIN3A_MOUSE (1-1273): 0: 1542: 98.04
+	Sc
		609105 RSC8_YEAST (336-751): 4.61e-104: 342: 28.30		SIN3_YEAST (20-499): 1.06e-32: 140: 14.02
+	Hs
		231905 KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15