Interactor 1: NPL4 (Q8TAT6)
Nuclear protein localization protein 4 homolog (Protein NPL4)
Gene: NPLOC4

Interactor 2: UFD1 (Q92890)
Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1)
Gene: UFD1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.759

The method score is based on:

Property Details
Experiments 26389662, 28320958, 18586029, 35920641, 36087575, 37071682, 17202270, 32296183, 11574150, 33961781, 16322459, 15371428, 24248593, unassigned1304, 20414249
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, cross-linking study, two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0030970 - retrograde protein transport, ER to cytosol
and 6 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 608
Hs

1 307
+ Rn
+ Xl
+ Dm
+ Sc
+ Ce
+ Ce
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024