HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25071155, 31048545
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 397
+	Hs
		125038 WWP2_HUMAN (1-870): 0: 982: 100.00		DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55
+	Hs
		681509 HUWE1_HUMAN (241-869): 7.77e-179: 575: 30.03		DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00
+	Hs
		243476 HUWE1_HUMAN (241-869): 7.77e-179: 575: 30.03		DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55
+	Hs
		1192168 HUWE1_HUMAN (241-869): 7.77e-179: 575: 30.03		DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93
+	Sc
		633515 TOM1_YEAST (494-869): 6.11e-158: 514: 40.26		MAS5_YEAST (1-396): 8.35e-140: 406: 45.37
+	Hs
		636367 HUWE1_HUMAN (241-869): 7.77e-179: 575: 30.03		DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59
+	Hs
		681610 SMUF1_HUMAN (1-385): 1.35e-45: 177: 17.77		DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00
+	Sc
		633244 RSP5_YEAST (16-376): 1.4e-39: 159: 18.39		MAS5_YEAST (1-396): 8.35e-140: 406: 45.37
+	Hs
		243651 HECW2_HUMAN (154-531): 5.96e-16: 84.8: 17.23		DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55