HitPredict

Interactor 1: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: NRCAM (Q92823)
Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (hBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related)
Gene: NRCAM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	22889411
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 728 Hs			1 1304
+	Hs
		1136434 MAGI3_HUMAN (258-722): 6.12e-18: 90.9: 11.75		NRCAM_HUMAN (1-1304): 0: 893: 100.00
+	Mm
		1195001 DLG1_MOUSE (331-728): 7.2e-29: 125: 17.16		NRCAM_MOUSE (1-1304): 0: 839: 89.88
+	Mm
		1143386 DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40		NRCAM_MOUSE (1-1304): 0: 839: 89.88
+	Hs
		1191159 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		SDK1_HUMAN (244-1160): 2.13e-83: 303: 14.86
+	Hs
		234553 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		DSCAM_HUMAN (3-961): 8.7e-59: 225: 11.77
+	Rn
		88569 D3ZWS0_RAT (356-722): 7.38e-28: 122: 16.84		D3ZDA6_RAT (342-1298): 1.69e-88: 319: 17.84
+	Mm
		524114 DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40		CNTN1_MOUSE (267-1229): 1.41e-95: 332: 15.82
+	Rn
		88572 DLG4_RAT (267-582): 6.83e-21: 99.8: 16.09		D3ZDA6_RAT (342-1298): 1.69e-88: 319: 17.84
+	Rn
		88571 MAGI2_RAT (121-422): 3.25e-17: 88.6: 11.22		D3ZDA6_RAT (342-1298): 1.69e-88: 319: 17.84
+	Rn
		88576 MAGI3_RAT (320-722): 1.69e-16: 86.3: 12.62		D3ZDA6_RAT (342-1298): 1.69e-88: 319: 17.84
+	Hs
		234511 DLG1_HUMAN (354-728): 3.16e-29: 126: 16.15		DSCAM_HUMAN (3-961): 8.7e-59: 225: 11.77
+	Hs
		234509 PTN13_HUMAN (455-725): 4.02e-23: 107: 15.44		DSCAM_HUMAN (3-961): 8.7e-59: 225: 11.77
+	Hs
		234499 DLG4_HUMAN (581-725): 3.01e-21: 100: 22.22		DSCAM_HUMAN (3-961): 8.7e-59: 225: 11.77
+	Hs
		234545 MAGI2_HUMAN (151-509): 8.26e-19: 93.6: 11.36		DSCAM_HUMAN (3-961): 8.7e-59: 225: 11.77
+	Hs
		234530 MAGI3_HUMAN (258-722): 6.12e-18: 90.9: 11.75		DSCAM_HUMAN (3-961): 8.7e-59: 225: 11.77
+	Hs
		1199785 MAGI2_HUMAN (151-509): 8.26e-19: 93.6: 11.36		DSCL1_HUMAN (4-955): 7.84e-54: 209: 11.93
+	Hs
		1136432 MAGI3_HUMAN (258-722): 6.12e-18: 90.9: 11.75		DSCL1_HUMAN (4-955): 7.84e-54: 209: 11.93
+	Mm
		936319 DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40		DCC_MOUSE (3-781): 2.31e-31: 136: 13.01
+	Hs
		1256852 PARD3_HUMAN (247-554): 1.39e-32: 137: 20.96		TITIN_HUMAN (519-838): 1.05e-12: 75.6: 12.15
+	Mm
		1143349 DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40		SDK2_MOUSE (736-1178): 7.02e-20: 99.1: 9.87