HitPredict

Interactor 1: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: ZBT8A (Q96BR9)
Zinc finger and BTB domain-containing protein 8A (BTB/POZ and zinc-finger domain-containing factor) (BTB/POZ and zinc-finger domains factor on chromosome 1) (BOZ-F1)
Gene: ZBTB8A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.608

Property	Details
Experiments	16189514, 29892012
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 441
+	Hs
		1252492 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		ZBT26_HUMAN (3-392): 1.41e-72: 236: 20.10
+	Hs
		200298 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		ZBT43_HUMAN (1-381): 2.85e-71: 234: 20.40
+	Hs
		1078406 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		ZKSC8_HUMAN (111-336): 5.9e-56: 196: 14.29
+	Hs
		196640 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		ZBT24_HUMAN (104-308): 2.69e-27: 116: 9.05
+	Hs
		1120791 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KLH12_HUMAN (4-125): 6.54e-16: 81.6: 35.25
+	Hs
		565093 SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52		ZNF7_HUMAN (131-440): 2.73e-123: 375: 15.88
+	Mm
		1145243 MPDZ_MOUSE (262-711): 2.29e-33: 140: 14.07		ZBT7B_MOUSE (1-398): 5.46e-78: 253: 19.31
+	Hs
		1049963 SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52		ZKSC8_HUMAN (111-336): 5.9e-56: 196: 14.29
+	Hs
		1050067 SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52		PATZ1_HUMAN (214-389): 2.37e-24: 107: 16.67