HitPredict

Interactor 1: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: KR412 (Q9BQ66)
Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12)
Gene: KRTAP4-12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.555

Property	Details
Experiments	16189514, 29892012
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 201
+	Hs
		1252458 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KRA42_HUMAN (34-166): 4.14e-20: 83.6: 48.12
+	Hs
		1252455 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KRA98_HUMAN (3-156): 1.25e-16: 75.2: 44.30
+	Hs
		889593 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KR108_HUMAN (54-201): 1.55e-15: 74.4: 32.68
+	Hs
		1252456 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KRA93_HUMAN (2-131): 4.33e-15: 71.3: 50.00
+	Hs
		1252457 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KRA92_HUMAN (4-131): 6.79e-14: 68.2: 46.88
+	Hs
		991628 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KRA11_HUMAN (89-201): 5.7e-11: 60.5: 30.99
+	Hs
		888597 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KR123_HUMAN (61-146): 9.75e-10: 55.5: 39.08
+	Hs
		1252459 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KRA24_HUMAN (40-165): 7.77e-09: 53.6: 38.58
+	Hs
		473321 LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00		KRA23_HUMAN (40-165): 7.77e-09: 53.6: 38.58
+	Mm
		82714 DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40		B9EJ72_MOUSE (6-193): 6.04e-33: 126: 17.76