HitPredict

Interactor 1: SHKB1 (Q8TBC3)
SH3KBP1-binding protein 1 (SETA-binding protein 1)
Gene: SHKBP1

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	35271311, 34315543
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 707 Hs			1 541
+	Hs
		1296975 KCTD3_HUMAN (3-657): 0: 992: 63.58		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		1075432 SHKB1_HUMAN (1-707): 0: 1175: 100.00		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		153935 SHKB1_HUMAN (1-707): 0: 1175: 100.00		NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89
+	Hs
		1132910 SHKB1_HUMAN (1-707): 0: 1175: 100.00		NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70
+	Hs
		67916 SHKB1_HUMAN (1-707): 0: 1175: 100.00		PDZ1P_HUMAN (38-282): 1.35e-15: 80.7: 14.23
+	Hs
		1075479 KCTD3_HUMAN (3-657): 0: 992: 63.58		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		153961 KCTD3_HUMAN (3-657): 0: 992: 63.58		NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89
+	Hs
		1132930 KCTD3_HUMAN (3-657): 0: 992: 63.58		NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70
+	Hs
		67925 KCTD3_HUMAN (3-657): 0: 992: 63.58		PDZ1P_HUMAN (38-282): 1.35e-15: 80.7: 14.23
+	Hs
		1300703 KCTD3_HUMAN (3-657): 0: 992: 63.58		MAGI1_HUMAN (2-334): 3.18e-13: 74.9: 17.51
+	Hs
		1296929 KCTD5_HUMAN (4-127): 2.47e-37: 141: 35.43		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		608227 KCNA4_HUMAN (13-231): 1.8e-39: 156: 16.46		SNTA1_HUMAN (1-188): 2.48e-29: 123: 20.10
+	Hs
		1075459 BACD3_HUMAN (1-200): 5.07e-42: 157: 24.26		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		1075465 KCTD5_HUMAN (4-127): 2.47e-37: 141: 35.43		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		153954 KCTD5_HUMAN (4-127): 2.47e-37: 141: 35.43		NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89
+	Dm
		439922 KCNAS_DROME (9-228): 1.32e-38: 154: 16.38		DLG1_DROME (44-160): 1.73e-12: 72.3: 19.49
+	Hs
		1132926 KCTD5_HUMAN (4-127): 2.47e-37: 141: 35.43		NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70
+	Hs
		67923 KCTD5_HUMAN (4-127): 2.47e-37: 141: 35.43		PDZ1P_HUMAN (38-282): 1.35e-15: 80.7: 14.23
+	Hs
		67909 KCTD2_HUMAN (13-124): 2.17e-36: 139: 41.53		PDZ1P_HUMAN (38-282): 1.35e-15: 80.7: 14.23
+	Mm
		761860 BACD1_MOUSE (5-162): 2.17e-37: 144: 25.63		ZO1_MOUSE (12-254): 1.04e-10: 66.8: 13.10