HitPredict

Interactor 1: SHKB1 (Q8TBC3)
SH3KBP1-binding protein 1 (SETA-binding protein 1)
Gene: SHKBP1

Interactor 2: KCTD3 (Q9Y597)
BTB/POZ domain-containing protein KCTD3 (Renal carcinoma antigen NY-REN-45)
Gene: KCTD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BTB_2~BTB_2
Common GO terms	GO:0051260 - protein homooligomerization
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 707 Hs			1 815
+	Hs
		1252618 SHKB1_HUMAN (1-707): 0: 1175: 100.00		SHKB1_HUMAN (14-661): 0: 1005: 65.46
+	Hs
		1252629 SHKB1_HUMAN (1-707): 0: 1175: 100.00		KCTD7_HUMAN (8-125): 5.48e-36: 139: 31.36
+	Hs
		1302211 KCTD3_HUMAN (3-657): 0: 992: 63.58		KCD15_HUMAN (3-183): 1.2e-43: 161: 24.47
+	Hs
		1174585 KCTD3_HUMAN (3-657): 0: 992: 63.58		KCTD1_HUMAN (8-183): 6.49e-43: 158: 21.86
+	Hs
		1297995 KCTD3_HUMAN (3-657): 0: 992: 63.58		KCTD7_HUMAN (8-125): 5.48e-36: 139: 31.36
+	Hs
		1273162 KCNB2_HUMAN (5-232): 2.36e-54: 203: 16.06		KCNG1_HUMAN (11-191): 3.48e-38: 151: 17.28
+	Hs
		1255150 KCNB2_HUMAN (5-232): 2.36e-54: 203: 16.06		KCNG4_HUMAN (7-191): 1.13e-36: 147: 19.59
+	Hs
		1058649 KCNB1_HUMAN (2-232): 4.64e-52: 196: 16.27		KCNG1_HUMAN (11-191): 3.48e-38: 151: 17.28
+	Hs
		1058643 KCNB1_HUMAN (2-232): 4.64e-52: 196: 16.27		KCNG4_HUMAN (7-191): 1.13e-36: 147: 19.59
+	Hs
		1116797 KCD21_HUMAN (17-207): 5.08e-52: 182: 29.95		KCD15_HUMAN (3-183): 1.2e-43: 161: 24.47
+	Hs
		1116784 KCD21_HUMAN (17-207): 5.08e-52: 182: 29.95		KCD21_HUMAN (17-148): 1.68e-40: 151: 34.06
+	Hs
		1308820 KCD14_HUMAN (2-240): 3.52e-59: 201: 23.75		KCD14_HUMAN (8-130): 5.79e-34: 132: 29.92
+	Hs
		558796 KCNA2_HUMAN (1-231): 1.12e-42: 163: 13.82		KCNG1_HUMAN (11-191): 3.48e-38: 151: 17.28
+	Hs
		1057246 KCND2_HUMAN (1-231): 1.9e-41: 162: 19.75		KCTD2_HUMAN (11-185): 1.92e-38: 145: 28.36
+	Hs
		1297982 KCTD7_HUMAN (2-228): 4.8e-46: 167: 27.16		KCTD7_HUMAN (8-125): 5.48e-36: 139: 31.36
+	Ce
		1353449 Q9TZA6_CAEEL (16-210): 6.08e-48: 170: 24.12		Q9TZA6_CAEEL (15-147): 1.29e-35: 136: 31.11
+	Hs
		1235382 KCND2_HUMAN (1-231): 1.9e-41: 162: 19.75		KCD17_HUMAN (18-180): 2.26e-36: 141: 32.62
+	Hs
		1116791 KCD21_HUMAN (17-207): 5.08e-52: 182: 29.95		KCTD6_HUMAN (17-109): 7.95e-30: 120: 45.26