Interactor 1: UBA3 (Q8TBC4)
NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3)
Gene: UBA3

Interactor 2: UBA3 (Q8TBC4)
NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3)
Gene: UBA3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.898

The method score is based on:

Property Details
Experiments 25416956, 10207026, 32296183, unassigned1304
Identification Methods two hybrid, enzymatic study, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains E2_bind~ThiF, ThiF~ThiF
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006508 - proteolysis
and 9 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 463
Hs

1 463
+ Hs
+ Hs
+ Hs
+ Sc
+ Zm
+ Sc
+ Hs
+ Oc
+ Sc
+ Sp
+ Cj

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Last updated: 15 Jul 2024