HitPredict

Interactor 1: DJB14 (Q8TBM8)
DnaJ homolog subfamily B member 14
Gene: DNAJB14

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33957083
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0030544 - Hsp70 protein binding GO:0071218 - cellular response to misfolded protein
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 379 Hs			1 303
+	Hs
		1348103 DJB12_HUMAN (1-378): 4.05e-127: 371: 50.79		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		213601 DJB14_HUMAN (1-379): 8.4e-133: 386: 100.00		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Hs
		213656 DJB12_HUMAN (1-378): 4.05e-127: 371: 50.79		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Mm
		1194952 DJB12_MOUSE (1-378): 4.62e-124: 364: 49.87		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22
+	Hs
		1333332 DJC18_HUMAN (44-379): 8.1e-86: 266: 45.95		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		213644 DJC18_HUMAN (44-379): 8.1e-86: 266: 45.95		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Hs
		279360 DNJB5_HUMAN (106-253): 1.4e-48: 169: 35.81		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		1290536 DNJA3_HUMAN (60-251): 1.68e-43: 158: 24.87		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		636443 DNJB1_HUMAN (106-371): 9.68e-44: 156: 24.55		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		1245931 DNJB8_HUMAN (108-267): 3.21e-44: 154: 34.36		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		636530 DNJB2_HUMAN (108-247): 1.07e-42: 153: 32.88		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		681648 DNJA1_HUMAN (105-209): 7.48e-17: 83.2: 48.57		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		1354291 DJB11_HUMAN (107-183): 9.32e-16: 79.7: 50.00		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Dm
		1366898 Q9VWL4_DROME (88-379): 6.6e-46: 166: 18.75		Q9VH81_DROME (4-246): 6.54e-32: 125: 16.87
+	Hs
		858603 DJB13_HUMAN (106-252): 3.41e-42: 151: 30.07		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Mm
		1194854 DNJA3_MOUSE (108-220): 5.93e-43: 157: 39.47		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22
+	Mm
		1194908 DNJB4_MOUSE (106-248): 1.51e-43: 155: 35.66		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22
+	Mm
		222727 DNJB6_MOUSE (108-250): 5.78e-43: 155: 33.12		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22
+	Hs
		636340 DNJB1_HUMAN (106-371): 9.68e-44: 156: 24.55		TOM34_HUMAN (26-117): 9.37e-11: 63.5: 35.87
+	Mm
		1194849 DJB11_MOUSE (107-183): 9.32e-16: 79.7: 50.00		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22