Interactor 1: R3GEF (Q8TBN0)
Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)
Gene: RAB3IL1

Interactor 2: RAB3I (Q96QF0)
Rab-3A-interacting protein (Rab3A-interacting protein) (Rabin-3) (Rabin8) (SSX2-interacting protein)
Gene: RAB3IP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 25416956, 26186194, 16189514, 28514442, 27173435, 33961781, 19060904
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, tandem affinity purification, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Sec2p~Sec2p
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0006887 - exocytosis
GO:0015031 - protein transport
GO:0070319 - Golgi to plasma membrane transport vesicle
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 382
Hs

1 476
+ Hs
+ Hs

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Last updated: 15 Jul 2024