HitPredict

Interactor 1: TBC15 (Q8TC07)
TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP)
Gene: TBC1D15

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.555

Property	Details
Experiments	33545068, 20562859
Identification Methods	proximity labelling technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 691 Hs			1 125
+	Hs
		891232 TBC15_HUMAN (1-691): 0: 692: 100.00		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306240 TBC15_HUMAN (1-691): 0: 692: 100.00		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1253202 TBC15_HUMAN (1-691): 0: 692: 100.00		MLP3C_HUMAN (1-120): 2.08e-51: 161: 55.00
+	Hs
		1253208 TBC15_HUMAN (1-691): 0: 692: 100.00		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		1326155 TBC17_HUMAN (1-644): 1.78e-176: 519: 47.45		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1330629 TBC17_HUMAN (1-644): 1.78e-176: 519: 47.45		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		1328034 TBC17_HUMAN (1-644): 1.78e-176: 519: 47.45		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Dm
		1364630 Q9VPL5_DROME (8-629): 2.78e-132: 408: 31.81		Q9VEG5_DROME (1-120): 1.37e-50: 158: 29.17
+	Hs
		1109689 TBC25_HUMAN (308-559): 4.74e-89: 294: 37.95		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1109691 TBC25_HUMAN (308-559): 4.74e-89: 294: 37.95		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		1252978 TBC16_HUMAN (271-667): 1.46e-87: 292: 28.88		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		891174 TBC25_HUMAN (308-559): 4.74e-89: 294: 37.95		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306201 TBC25_HUMAN (308-559): 4.74e-89: 294: 37.95		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1109688 TBC25_HUMAN (308-559): 4.74e-89: 294: 37.95		MLP3C_HUMAN (1-120): 2.08e-51: 161: 55.00
+	Hs
		1109690 TBC25_HUMAN (308-559): 4.74e-89: 294: 37.95		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		1170416 TBCD9_HUMAN (196-659): 2.96e-80: 279: 13.53		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1252977 TBC16_HUMAN (271-667): 1.46e-87: 292: 28.88		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		1117431 TB10B_HUMAN (212-670): 5.71e-83: 281: 15.92		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		891196 TBCD9_HUMAN (196-659): 2.96e-80: 279: 13.53		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		1117430 TB10B_HUMAN (212-670): 5.71e-83: 281: 15.92		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46