Interactor 1: HM13 (Q8TCT9)
Minor histocompatibility antigen H13 (EC 3.4.23.-) (Intramembrane protease 1) (IMP-1) (IMPAS-1) (hIMP1) (Presenilin-like protein 3) (Signal peptide peptidase)
Gene: HM13

Interactor 2: DERL1 (Q9BUN8)
Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1)
Gene: DERL1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.612

The method score is based on:

Property Details
Experiments 25239945, 34079125
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, blue native page
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0031625 - ubiquitin protein ligase binding
GO:0036513 - Derlin-1 retrotranslocation complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 377
Hs

1 251
+ Zm
+ Sc

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Last updated: 15 Jul 2024