HitPredict

Interactor 1: SP7 (Q8TDD2)
Transcription factor Sp7 (Zinc finger protein osterix)
Gene: SP7

Interactor 2: SORL (Q92673)
Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA)
Gene: SORL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.50	0.565

Property	Details
Experiments	33961781, 35140242
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 2214
+	Hs
		1110302 SP6_HUMAN (67-376): 9.74e-93: 286: 39.51		SORL_HUMAN (1-2214): 0: 1927: 100.00
+	Hs
		1237395 ZN713_HUMAN (202-358): 1.28e-45: 165: 24.12		SORL_HUMAN (1-2214): 0: 1927: 100.00
+	Hs
		254304 ZN214_HUMAN (178-429): 5.75e-98: 307: 18.97		LRP4_HUMAN (1350-1709): 2.47e-19: 98.1: 15.51
+	Hs
		435042 SP1_HUMAN (195-410): 2.85e-40: 155: 46.30		LRP2_HUMAN (1316-1712): 1.36e-18: 95.8: 17.49
+	Hs
		270295 ZKSC8_HUMAN (95-300): 1.88e-49: 178: 11.68		LRP6_HUMAN (1445-1549): 6.8e-11: 70.1: 36.94
+	Hs
		254280 ZN248_HUMAN (296-430): 2.36e-17: 86.2: 14.29		LRP4_HUMAN (1350-1709): 2.47e-19: 98.1: 15.51
+	Hs
		254278 ZN383_HUMAN (46-218): 1.26e-09: 62: 10.92		LRP4_HUMAN (1350-1709): 2.47e-19: 98.1: 15.51
+	Hs
		270315 ZN383_HUMAN (46-218): 1.26e-09: 62: 10.92		LRP6_HUMAN (1445-1549): 6.8e-11: 70.1: 36.94
+	Hs
		258331 ZN383_HUMAN (46-218): 1.26e-09: 62: 10.92		LRP5_HUMAN (1445-1549): 8.69e-11: 69.7: 37.27