HitPredict

Interactor 1: DLG5 (Q8TDM6)
Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG)
Gene: DLG5

Interactor 2: DYL2 (Q96FJ2)
Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8b) (Dynein light chain LC8-type 2)
Gene: DYNLL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1919 Hs			1 89
+	Hs
		928408 DLG5_HUMAN (1-1919): 0: 936: 100.00		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Rn
		928570 DLG3_RAT (1133-1916): 0: 573: 19.56		DYL1_RAT (1-89): 1.8e-47: 147: 93.26
+	Mm
		928550 DLG4_MOUSE (1177-1916): 2.2e-156: 500: 20.46		DYL1_MOUSE (1-89): 1.8e-47: 147: 93.26
+	Hs
		928259 DLG4_HUMAN (1177-1916): 3.58e-156: 499: 20.46		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		942366 DLG4_HUMAN (1177-1916): 3.58e-156: 499: 20.46		DYL2_HUMAN (1-89): 7.09e-47: 146: 100.00
+	Hs
		928313 DLG2_HUMAN (1165-1916): 1.63e-152: 494: 19.10		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		1077286 DLG2_HUMAN (1165-1916): 1.63e-152: 494: 19.10		DYL2_HUMAN (1-89): 7.09e-47: 146: 100.00
+	Hs
		928507 ZO2_HUMAN (1470-1802): 2.6e-11: 71.2: 13.01		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26